| Tab. 2 – Dávkování léčiv při chronickém selhání ledvin a chronické renální insuficienci (úprava dávkovacího intervalu h, nebo % dávky) | |||||
| Léčivo | Renální | GF > 50 | GF 10–50 | GF < 10 | Poznámka |
| exkrece (%) | (ml/min) | (ml/min) | (ml/min) | ||
| ACE-inhibitory | 50–70 | N | 50–75 % | 25–50 % | hyperkalémie, NÚL |
| Acebutolol | 55 | N | 50 % | 25 % | aktivní metabolity |
| Acetazolamid | 100 | 6 | 12 | nepodávat | metabolická acidóza |
| Acetylsalicylová kyselina | 10 | 4 | 4–6 | nepodávat | |
| Acyklovir (i. v.) | 40–70 | 6 | 24 | 48 | |
| Alendronát sodný | 50 | N | nepodávat | nepodávat | |
| Allopurinol | 50 | N | 50 % | 10–25 % | NÚL |
| Amantadin | 90 | 12–24 | 24–72 | 72–168 | |
| Amfotericin B | 5 | 24 | 24 | 24–36 | poškození ledvin |
| Amilorid | 50 | 12–24 | nepodávat | nepodávat | hyperkalémie |
| Aminoglykosidy | > 90 | 8–12 | 12 | > 24 | monitorování hladin |
| Amoxicilin | 86 | 8 | 8–12 | 12–24 | |
| Ampicilin | 82 | 6 | 6–12 | 12–16 | |
| Atenolol | < 90 | N | 50 % | 25 % | |
| Aztreonam | 75 | N | 50-75 % | 25 % | |
| Betaxolol | 15 | N | N | 50 % | |
| Bretylium | 75 | N | 25–50 % | nepodávat | |
| Cefadroxil | 70–90 | 12 | 12–24 | 24–48 | |
| Cefalexin | 90 | 6 | 6 | 8–12 | |
| Cefalotin | 60–90 | 6 | 6–8 | 12 | |
| Cefazolin | 80 | 8 | 12 | 24–48 | |
| Cefepim | 80 | 12 | 24 | 25 %, 24 h | |
| Cefixim | 20–50 | 12–24 | 75 % | 50 % | |
| Cefotaxim | 50–60 | 6–8 | 8–12 | 24 | |
| Cefoxitin | 77–90 | 8 | 8–12 | 24–48 | |
| Cefpodoxim | 30 | 12 | 16 | 24–48 | |
| Ceftazidim | 60 | 8–12 | 24–48 | 48–72 | |
| Ceftriaxon | 30–65 | N | N | 24 | |
| Cefuroxim | > 90 | N | 12 | 24 | |
| Cetirizin | 50 | N | 50 % | 50 % | |
| Cimetidin | 40–70 | 6 | 8 | 12 | |
| Ciprofloxacin | 50–70 | N | 12–24 | 24 | |
| Didanosin | 40 | 12 | 24 | 48 | |
| Digoxin | 76–85 | 24 | 36 | 48 | monitorování hladin |
| Disopyramid | 50–60 | 75 % | 25–50 % | 10–25 % | |
| Doxycyklin | 33–45 | 12 | 12–18 | 18 24 | kumulace metabolitů |
| Ethambutol | 75–90 | 24 | 24–36 | 48 | |
| Ethosuximid | N | N | 75% | ||
| Famcyklovir | metabolit | 8 | 12–24 | 48 | |
| Famotidin | 80 | N | N | 50 % | |
| Fenobarbital | N | N | 12-16 | ||
| Flucytosin | > 90 | 6 | 24 | 24-48 | |
| Flukonazol | 70 | N | 50 % | 25 % | |
| Gancyklovir | 95–100 | 12 | 24 | 24 | |
| Gemfibrozil | < 10 | N | 50 % | 25 % | |
| Hydralazin (p. o.) | 25 | 8 | 8 | 8–16 | |
| Hydrochlorothiazid | > 95 | N | N | nepodávat | |
| Chlortalidon | 50 | 24–48 | nepodávat | nepodávat | |
| Imipenem | 20–70 | N | 50 % | 25 % | |
| Indapamid | 7 | N | N | nepodávat | |
